Saudi Arabia has detained 10 princes and dozens of former ministers through its newly formed anti-corruption committee, Saudi-owned Al Arabiya TV reported, citing unnamed sources.
The new committee, headed by Crown Prince Mohammed bin Salman, was formed by royal decree hours earlier on Saturday.
Those sacked include Prince Meteb bin Abdullah, the head of the National Guard, and Adel Fakeih, the economy minister.
Abdullah al-Sultan, commander of the Saudi navy, was replaced by Fahad al-Ghafli.
No official explanation was given for the dismissals.
The changes come just months after Saudi King Salman bin Abdulaziz Al Saud replaced his nephew Mohammed bin Nayef with his son Mohammed bin Salman as the kingdom's crown prince.
Mohammed bin Salman has been responsible for pushing through a number of changes both at home and abroad since he became first in line to the Saudi crown.