One protester was killed on Monday by security forces in the Sudanese capital, Khartoum, Anadolu News Agency reports.
An unidentified protester was fatally shot in the chest, said the Central Committee of Sudanese Doctors in a statement.
Fresh protests erupted in Sudan on Monday to demand full civilian rule amid UN-mediated talks to salvage the country's transition to democracy.
Hundreds of protesters marched to the presidential palace in Khartoum, chanting against the military, according to an Anadolu Agency reporter at the scene.
Demonstrators rejected UN mediation to solve the country's political crisis, blasting the effort as an attempt to save the military.
'Army has to hand over power immediately'
"The Sudanese can solve their problems alone," Abdul Rahim Ahmed, a protester in Khartoum said.
"This initiative of the UN envoy aims to save the army generals and enable them to get immunity from justice for their constant killings of protesters," he added.
Last week, seven protesters were killed in anti-military protests in crisis-hit Sudan.
Earlier this month, the UN mission in Sudan launched UN-facilitated talks between the military and political groups to salvage the Horn of African country's transition.
"We will not sit with the army under the initiative of the UN or any other forum," said Mona Hussein, another protester. "The army has to hand over power to civilians immediately," she added.
Sudan has been in turmoil since 25 October, 2021, when the military dismissed Prime Minister, Abdalla Hamdok's transitional government and declared a state of emergency.
Before the military takeover, Sudan was governed by a sovereign council of military and civilian officials tasked with overseeing the transition period until elections in 2023.
Hamdok was reinstated on 21 November, following an agreement, but protesters denounced the deal, insisting on the removal of any military influence over the transitional governing coalition. He resigned on 2 January, citing a political deadlock.